Harry Malech, M.D.

Dr. Malech is currently Chief of the Genetic Immunotherapy Section (GIS), and Deputy Chief of the Laboratory of Clinical Immunology and Microbiology (LCIM) at the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID). The mission of GIS is the development of gene therapy and hematopoietic stem cell transplantation approaches to the treatment of a variety of inherited primary immune deficiencies. Associated with that mission is the diagnosis and treatment of the infections, inflammation, autoimmunity, pulmonary dysfunction, and growth failure that may complicate management of a number of primary immune deficiencies. He has overseen clinical trials of gene therapies that use ex vivo transduction of autologous hematopoietic stem cells, as well as studies of allogeneic HSC transplantation for rare diseases.

Dr. Malech received his medical degree from Yale University in New Haven, Connecticut. He completed clinical residency training at the University of Pennsylvania in Philadelphia, followed by basic research postdoctoral fellowship training at the National Institutes of Health (NIH) in Bethesda, Maryland. After then completing clinical fellowship training in infectious diseases at Yale University, he remained at Yale as assistant and then associate professor. In 1986, he returned to NIH as a senior investigator in NIAID.